Donna Haraway, 2004:

"...knowledge is always an engaged material practice and never a disembodied set of ideas. Knowledge is embedded in projects; knowledge is always for, in many senses, some things and not others, and knowers area always formed by their projects, just as they shape what they can know. Such shapings never occur in some unearthly realm; they are always about the material and meaningful interactions of located humans and nonhumans -machines, organisms, land, institutions, money, and many other things. Because scientific knowledge is not ‘transcendent,’ it can make solid claims about material beings that are neither reducible to opinion nor exempt from interpretation. Those solid claims and material beings are irreducibly engaged in cultural practice and practical culture; i.e., in the traffic in meanings and bodies, or acts of love, with which all things begin. Semiosis is about the physiology of meaning-making..."

-Donna Haraway (2004:199-200), “Morphing in the Order: Flexible Strategies, Feminist Science Studies, and Primate Revisions" 199-222 in The Haraway Reader.  Routledge New York 2004.